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Research Newsletter
CWRU ORA - News and Funding Opportunities
April 21, 2017  

Funding Opportunities

Alzheimer's Drug Discovery Foundation - Pre-Clinical Drug Discovery Program
Grants of up to $600,000 over two years will be awarded in support of promising preclinical drug discovery programs relevant to Alzheimer’s disease, related dementias, and cognitive aging. Preclinical research funding priorities include high through-put screening, medicinal chemistry hit-to-lead development (and lead optimization), in vitro and in vivo efficacy studies, ADME, toxicology, pharmacokinetics and pharmacodynamics, and in vivo proof-of-concept with lead compounds and biologics.

Program areas of particular interest include new chemical compounds for Alzheimer's disease, preclinical proof-of-concept, and re-purposing. With regards to potential drug targets, ADDF is interested in novel targets that include but are not limited to neuroinflammation, protein degradation/autophagy, growth factor signaling, synaptic function/morphology, calcium regulation, energy utilization/mitochondria function, insulin sensitivity, epigenetics, ApoE function and cholesterol metabolism, vascular injury and the blood-brain barrier interface, cognitive enhancers, myelin changes, ischemia and oxidative stress, and tau-related toxicities.

To be eligible, applicants must be an academic investigator seeking to create and support an innovative translational program in an academic medical center or university; a biotechnology company with programs dedicated to Alzheimer's disease translational development; or a new biotechnology company spinout or existing biotechnology company with a clear need for nonprofit funding. Funding is provided through program-related investments (PRIs) that require return on investment based on scientific and/or business milestones.

Letter of Intent Deadline: May 19, 2017
Invited Proposal Deadline: June 09, 2017

For more information visit the ADDF website.

DHHS – NIH - Expanding Medication Assisted Treatment for Opioid Use Disorders in the Context of the SAMHSA Opioid STR Grants (R21/R33)
The purpose of this FOA is to solicit applications proposing to test approaches for expanding medication assisted treatment (MAT) for opioid use disorder (OUD) in the general health care sector or linking individuals with OUDs who receive naloxone for the reversal of overdose to MAT in the context of states’ plans for use of the funds authorized under the 21st Century Cures Act.

Letter of Intent Deadline: 30 days prior to application due date
Applications/AIDS Application Deadline: June 20, 2017

For more information visit the NIH webpage.

J.M. Kaplan Fund
Through its Furthermore program, the J.M. Kaplan Fund supports nonfiction book publishing about the urban experience; natural and historic resources; art, architecture, and design; cultural history; and civil liberties and other public issues.

The program seeks work that appeals to an informed general audience; demonstrates evidence of high standards in editing, design, and production; promises a reasonable shelf life; might not otherwise achieve top quality or even come into being; and "represents a contribution without which we would be the poorer."

Individual grants will range from $1,500 to approximately $15,000 and may be used to support writing, research, editing, design, indexing, photography, illustration, and/or printing and binding. Applicants must be a 501(c)(3) organization. Trade publishers and public agencies may apply for grants in partnership with an eligible nonprofit sponsor.

Application Deadline: September 1, 2017

For more information visit the Furthermore webpage.

Kress Foundation - Digital Resources
The Digital Resources program is intended to foster new forms of research and collaboration as well as new approaches to teaching and learning. Support will also be offered for the digitization of important visual resources (especially art history photographic archives) in the area of pre-modern European art history; of primary textual sources (especially the literary and documentary sources of European art history); for promising initiatives in online publishing; and for innovative experiments in the field of digital art history. Please note that this grant program does not typically support the digitization of museum object collections.

  • Supports efforts to integrate new technologies into the practice of art history and the creation of important online resources in art history, including both textual and visual resources.
  • This grant program does not typically support the digitization of museum object collections.
  • Grants are award to non-profit institutions with 501(c) 3 status, based in the United States, including supporting foundations of European institutions.
  • These are competitive grants. Please see ‘Past Grants’ and ‘Annual Reports’ for past awards and typical levels of funding and review our Grants FAQs for answers to common application questions.
  • In addition to submitting printed materials, applicants must also email a digital copy of their application to This digital submission should be sent as a single PDF document.
Application Deadline: October 1, 2017

For more information visit the Kress Foundation website.

PCORI - Pipeline to Proposals Tier A Funding
The Patient-Centered Outcomes Research Institute (PCORI) works to improve healthcare delivery and outcomes through the production and promotion of high-integrity, evidence-based research guided by patients, caregivers, and the broader healthcare community.

To that end, the institute has issued a Request for Proposals for its Pipeline to Proposal Awards program to help individuals form new collaborations with the goal of developing proposals characterized by sound scientific rigor and robust patient engagement. The program is interested in research teams that, in addition to researchers, include patients, caregivers, clinicians, and other healthcare stakeholders.

The P2P program has two tiers. Tier A is designed to support the development of research partnerships as they identify a comparative clinical effectiveness research (CER) question (or series of questions) that is important to patients, researchers, and other members of the healthcare community. Tier B is designed to help research partnerships refine their CER questions and prepare an application for research funding.

For Tier A, PCORI is interested in receiving applications from individuals who are not usual candidates for research funding. To qualify, applicants must have demonstrated success in a past community-building project. (That success does not necessarily have to be in the field of health.) Tier A awards — up to $5,000 over a twelve-month term — are intended to fund the building of a partnership and skills necessary to develop a patient-centered CER project and can be used to fund activities that lead to the development of research capacity, new partnerships, and the infrastructure needed to conduct research. Eligible activities include workshops, roundtables, conferences, meetings, and other information-sharing tasks. Awardees will be expected to generate a list of CER questions that address the health issue of interest to those in the partnership.

Letter of Intent Deadline: April 20, 2017
Invited Proposal Deadline: June 30, 2017

For more information visit the PCORI website.

Wildlife Acoustics - Bio-acoustic Research
Wildlife Acoustics’ mission is to support efforts in conservation and environmental stewardship. The international organization aims to enable those involved in animal biology, research and conservation to do their best work easily and quickly.

To advance this mission, Wildlife Acoustics will award grants of up to $5,000 to support bioacoustics research efforts from chiropteran, avian, terrestrial, amphibious, and marine wildlife, to everything else in between. Projects must make significant use of bioacoustics for data collection and/or analysis and advance scientific knowledge and contribute to long-term conservation. In addition, the grant award must have a significant impact on the success of the project.

To be eligible, applicants must be biologists, researchers, conservationists or students who work for tax exempt, nonprofit organizations, educational institutions, or government agencies. Non-U.S. organizations are eligible to apply.

Application Deadline: May 15, 2017

For more information visit the Wildlife Acoustics webpage.

NEW Limited Submission: CWRU Technology Validation & Start-Up Fund Program (CTP)
The CWRU Technology Transfer Office (TTO) has been awarded a grant by the State of Ohio to fund the CTP. The terms and conditions of the award have not been finalized. In the interest of keeping the process moving while we await final terms, we are accepting pre-proposals.

Key Deadlines:
  • Pre-Proposal due April 19th, 2017, 5:00pm (using attached form)
  • Qualified proposals will be chosen to advance to the full-proposal stage. The deadline for full proposals is May 5th, 2017, 5:00pm.
The Technology Validation and Start Fund (TVSF), funded by the Ohio Third Frontier, aims to accelerate and fund the translation of promising technologies into the marketplace through Ohio start-up companies with the eventual goal of creating greater economic growth. In October 2016, CWRU was awarded a $500,000 fund, which will be administered by the Technology Transfer Office as the CWRU TVSF Program (CTP) to advance a number of selected programs over a 12-month period. As a result of this award CWRU investigators are no longer eligible to apply for TVSF funding directly to the State of Ohio, but must instead apply to this internal competition.

The CTP is intended to be the final bridge between a translational research project and a viable commercial program. Funding will support technologies that require validation/proof that will directly impact and enhance commercial viability and the ability to support a start-up company. Projects must have already advanced beyond basic research and should have the equivalent of a laboratory-scale proof of concept prior to applying for funding.

Applicants are encouraged to work with potential Ohio licensees and business advisors prior to submitting an application in order to identify critical needs for the technology. Paramount importance will be placed on customer discovery, whether in the form of industry partners or potential end users. Specific milestones related to enhancing valuation and reducing risk should be defined, which can include any of the following:

  • Prototyping, scale-up, animal and/or clinical testing, addressing regulatory or reimbursement requirements
Technology Focus Areas:

All proposals must fall into the State of Ohio’s technology focus areas below:

  • Biomedical/Life Sciences
  • Advanced Materials
  • Energy
  • Software/Information Technology
  • Sensors
  • Advanced Manufacturing
Anticipated award type: Standard Grant with 1:1 cost match required by applicant

Anticipated number of awards: 10 -12 per year at $50,000 - $100,000 each (includes cost match)

Total CTP funding amount: $500,000 + $500,000 cost match by awardees

Number of RFP’s: 3 per year (anticipated dates*: December 2016, April 2017, September 2017) * RFP dates subject to change

Funding period per project: 1 year

Funding start date: 1-2 months after submission of full proposal

Cost Match Requirement: cash cost share commitment of at least one dollar for every dollar of project funds requested (i.e., a ratio of 1:1) and must represent a specific new unrestricted cash commitment to the project.

For more information on this limited submission opportunity, visit the Office of Research Administration website.

Limited Submission Reminder: Edward Mallinckrodt, Jr. Foundation: Mallinckrodt Grants Applications

Key Deadlines: April 21, 2017, 5:00pm (CWRU Letter of Intent), August 1, 2017, 5:00pm EST (external application).

The Edward Mallinckrodt, Jr. Foundation is a private foundation that funds basic biomedical research in St Louis and throughout the United States.

Mallinckrodt Grants are competitively provided to investigators based on their proposals, selected from applicants on an annual basis. These awards are usually $60,000 per year for three years, provided an annual progress report is submitted and approved.

The mission of the Foundation is to support early stage investigators engaged in basic biomedical research that has the potential to significantly advance the understanding, diagnosis or treatment of disease.

Number of Applications Allowed: One

For more information on this limited submission opportunity, visit the Office of Research Administration website.

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Learn more about how to use all the features Pivot has to offer.

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